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Parathyroid Glands 

The parathyroid glands are four small glands located in the neck that help balance and regulate the calcium levels in the human body. Most of the diseases of the parathyroid glands are benign but can cause severe symptoms and medical problems if not treated properly. Disease of the parathyroid gland is often related to severe osteoporosis and/or multiple kidney stones. Many patients are also diagnosed by having an increased blood calcium level found on routine laboratory tests. 

 

As with thyroid surgery, the surgeon’s experience and expertise are highly valued in the treatment of parathyroid disease. Dr. Smith performs between 80-100 parathyroid operations each year and many of these surgeries can be performed through an incision that is less that one inch long and is done on an outpatient basis. This Minimally Invasive Parathyroid Surgery (MIPS) can be done in almost all patients with parathyroid disease. The outpatient surgery on parathyroid glands allows the patient to recuperate in the comfort of his/her own home. Dr. Smith was one of the first surgeons in the area to extensively use Intraoperative Parathyroid Hormone Monitoring. This technique along with minimally invasive parathyroid surgery gives the patient the greatest opportunity for cure with the least invasive surgical procedure.

Hyperparathyroidism

Primary hyperparathyroidism is a disease state that is manifested by an increased serum level of calcium and parathyroid hormone (PTH). The disease can affect any person between the ages of infancy til death. It is most common between 50 and 60 years of age and does have a three to one ratio in women versus men. Most patients are diagnosed with hypercalcemia on a routine physical examination. Further work up will then lead to the discovery of an increased PTH level and diagnosis of primary hyperparathyroidism. Symptoms involved in hyperparathyroidism may range from fatigue, memory loss, joint and muscle aches and pains, renal stones, and osteoporosis or softening of the bones.

Calcium in our body is found in the blood stream and bones and, when our parathyroid glands are functioning normally this balance is maintained. When hyperparathyroidism exists too much PTH causes too much calcium to be removed from our bones and put into our blood stream, thereby, creating the symptom complex mentioned above.

The most common cause of hyperparathyroidism is a benign enlargement of one parathyroid gland and this is referred to as a parathyroid adenoma. The second most common cause of hyperparathyroidism is referred to as parathyroid hyperplasia. This condition makes up approximately 15% of patients with primary hyperparathyroidism and in this condition all four parathyroid glands are enlarged. Carcinoma of the parathyroid glands is an extremely rare condition and occurs in less than 0.5% of cases.

During the past 10 years pre-operative parathyroid imaging has been developed to a much higher degree of specifity than was ever thought possible. Pre-operative sestimibi parathyroid scans are now routinely done on all patients and can successfully predict the location of the abnormal parathyroid gland in 70-80% of patients.

Dr. Smith was also one of the pioneers of the use of Intra Operative Parathyroid Hormone Monitoring (IOPTH) in this area of the country. This technique is used in combination with the Minimally Invasive Parathyroid Surgery to assure the greatest accuracy in the outcome of the patient’s parathyroid exploration.  IOPTH monitoring and Minimally Invasive Parathyroid Surgery has revolutionized the treatment of hyperparathyroidism and Dr. Smith has been on the forefront of these new and exciting techniques.

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